Altab Khan1, Mohd Riyaz Beg2*, Pramod Waghmare2
1. DBT-ICT Centre for Energy Biosciences, Institute of Chemical Technology, Mumbai 400019, Maharashtra, India
2. Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Mumbai 400019, Maharashtra, India
*Corresponding Author: Mohd Riyaz Beg
Address: Dept. of Pharm. Sci. & Tech., Institute of Chemical Technology, Mumbai 400019,Maharashtra, India
The use of low intensity ultrasound has gotten surprising consideration over the last decade as a method for enhancing the catalytic activity of enzyme.Ultrasounds have the potential to significantly influence the activity of the enzymatic processes, provided that the energy input is not too high to inactivate the enzyme.By providing the variation in parameters, various physical and chemical effects can be attained that can enhance the enzymatic reaction. Ultrasonic reactors are known for their application in bioprocesses.However, the potential of their applications is still limited broadly due to the lack of proper information about their operational and performance parameters.In this review, the detailed information aboutultrasonic reactorsis provided by definingthe different types of reactors, number and position of ultrasonic transducers. Also, it includes mechanism of intensification and influence of ultrasonic parameters (intensity, duty cycle and frequency) and enzymatic factors (enzyme concentration, temperature and pH) on the catalytic activity of enzyme during ultrasound treatment.
Keywords: Ultrasound, Ultrasonic reactors, Enzyme kinetic, Enzymatic reaction, Sonochemical reaction